Genetics of Heart & Vascular Disease

COURSE LOCATION
Hilton Los Cabos                                                                                                                    
Carretera Transpeninsular Km. 19.5 Cabo Real 
San Jose del Cabo, BCS 23400

COURSE DESCRIPTION
This program will be presented live in-person in San José del Cabo, Mexico.

During this 3 day CME course, experts in the field of genetic cardiology and cardiovascular genetics detail the important role of genetics, genomics, and pharmacogenetics in the diagnosis, risk stratification, and treatment of monogenetic, oligogenetic, and polygenic diseases affecting the heart and the blood vessels.

Topics covered will include genetics and genomics 101, pharmacogenetics, polygenic risk scores, variant interpretation, the diagnostic, prognostic, & therapeutic implications of genetic testing for patients with congenital heart disease, long QT syndrome, Brugada syndrome, hypertrophic/dilated/arrhythmogenic cardiomyopathy, coronary heart disease, hyperlipidemias, heart failure, pulmonary hypertension, cardiac amyloid, and the aortopathies, the state of the molecular autopsy, and the state of gene therapy for CV diseases.

COURSE LEARNING OBJECTIVES
Upon conclusion of this program, participants should be able to:

• Summarize the probabilistic nature of genetic testing
• Develop a strategy to manage the variant of uncertain significance (VUS) test result
• Identify the impact of genetic testing in the diagnosis, risk stratification, and treatment of patients with heritable cardiomyopathies, channelopathies, pulmonary hypertension, cardiac amyloidosis, and aortopathies 
• Determine the role of genetic testing in children and adults with congenital heart disease
• Define genetic markers of atherosclerosis and the role of genetic risk scores (GRS) in risk stratification of coronary heart disease
• Identify the genetic basis of heritable lipid disorders, implications for prevention and familial screening
• Define the role of pharmacogenetics in cardiovascular drug response, including the role of testing

Attendance at this Mayo Clinic course does not indicate nor guarantee competence or proficiency in the performance of any procedures which may be discussed or taught in this course.

INTENDED AUDIENCE
This course is intended for both pediatric and adult cardiologists, internists, primary care providers, PAs, nurse practitioners, nurses, pharmacists, pediatric and adult cardiology trainees, genetic counselors, and medical students with an interest in the management of patients with genetically mediated heart and vascular disease.