Abnormal diastolic filling of the heart plays a major role in producing the signs and symptoms of heart failure. It is essential to understand the underlying pathophysiology of diastolic function, including its progression from normal to relaxation to compliance abnormalities. Doppler echocardiography can be used to evaluate normal and abnormal diastolic filling of the heart. This information can then be applied to the diagnosis and treatment of patients with diastolic dysfunction, particularly those with “heart failure and preserved ejection fraction”.
- Describe the pathophysiologic mechanism of diastolic filling of the heart
- Use Doppler echocardiography to determine the status of diastolic filling of the heart
- Apply the findings from Doppler echocardiography to the management of patients with heart failure due to diastolic dysfunction
Rick Nishimura, M.D.
Professor of Medicine
Division of Cardiovascular Diseases
Mayo Clinic, Rochester, MN
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